A University of Manitoba study suggests artificial sweeteners are linked to the risk of long-term weight gain, heart disease and other health issues.
The study, published in the Canadian Medical Association Journal, says more people are eating and drinking artificial sweeteners such as aspartame, sucralose and stevia.
The university found new data indicating artificial sweeteners may have negative effects on metabolism, gut bacteria and appetite.
Author Ryan Zarychanski says despite the fact millions of individuals routinely consume artificial sweeteners, relatively few patients have been included in clinical trials of the products.
The research reviewed 37 studies that followed more than 400.000 people for an average of 10 years.
Until the long-term effects of artificial sweeteners are proven, the study recommends people be cautious about how much they are eating and drinking.